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Hydroquinone 2-4%, the gold standard treatment, requires once or twice daily application with direct tyrosinase inhibition

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[DOI] [PubMed] [Google Scholar] 57.Bauer K.C., Huus K.E., Brown E.M., Bozorgmehr T., Petersen C., Cirstea M., Woodward S.E., McCoy J., Hun J., Pamplona R