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Wagers told me, “Different groups have reported that amounts of GDF11 go up, go down, or stay the same with age.” With a bleak laugh, she added, “Clearly, one group is right.” After Rando’s colleague Tony Wyss-Coray showed that young blood can foster new neurons in the hippocampus region of the brains of old mice, a company called Alkahest spun out from his work

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These compounds exhibit antifungal properties primarily by compromising the integrity of the fungal cell membrane (inhibiting ergosterol synthesis), increasing permeability and decreasing ATPase activity (Yu, 2025