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The compound has been characterised across multiple research streams covering NNMT enzyme inhibition mechanism, adipocyte and obesity research, methyl-donor pool conservation, NAD+ pathway research, cancer-research framings (NNMT overexpression in tumours)

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Discussion This work uncovers a previously unappreciated role for BDNF-TrkB signalling in regulating cellular metabolic pathways, such as glutathione–ascorbate and energy metabolism