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Effect of Glutathione Infusion on Leg Arterial Circulation, Cutaneous Microcirculation, and Pain-Free Walking Distance in Patients With Peripheral Obstructive Arterial Disease: A Randomized, Double-Blind, Placebo-Controlled Trial - Mayo Clinic Proceedings

Treatment: if necessary, symptomatic treatment is carried out

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They require professional administration and have established (though sometimes contested) evidence bases