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The chromatographic system consisted of a binary solvent delivery system (LC-20AB), a degasser (DGU-20A3), an autosampler (SIL-20ACHT), a column temperature controller (CTO-10AS VP), and a photodiode array detector (SPD - M20 A) for CYP2C9 metabolites and fluorescence detector (RF-10A XL ) for CYP2D6 metabolites

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Gastrodin (GAS) is an active ingredient extracted from the plant Gastrodiae gastrodiae , and can be used to treat kidney injury