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Multifaceted clinical spectrum of Vitamin B12 deficiency | JBM | Dove Medical Press

Variations, especially in foods of plant origin, could be attributed to factors such as plant varieties and cultivars, growing conditions (e.g., season and climate), and agronomic practices (e.g., harvest time and postharvest handling)

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Evidence Evidence that CFS/ME patients are low in methylation cycle metabolites: B vitamin evidence In a small study of 58 chronic fatigue syndrome patients with a history of Epstein-Barr infection and B-cell immunodeficiency, 81% responded to folinic acid