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Dosage Calculation (TI): TD 50 /ED 50 The higher the TI, the safer the drug Potency curves Potency is determined by the affinity of a drug for its receptor Receptor Receptors are proteins located either on the surface of or within a cell that can bind to signaling molecules known as ligands (e.g., hormones) and cause some type of response within the cell

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Significant separation was also observed between the Model and SAC groups (Fig

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