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In a 48-week phase 2 study of retatrutide involving 338 overweight or obese non-diabetic participants, researchers observed dose-dependent decreases in weight and improvements in waist circumference, blood pressure, levels of glycated hemoglobin, fasting glucose and insulin, and most lipid metrics

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Demographic and general baseline characteristics are represented as LS-means with standard deviations for normally distributed parameters or medians with IQR for non-normally distributed parameters