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In their 2015 review in BioMed Research International, Pickart, Vasquez-Soltero and Margolina report that the plasma level of the GHK tripeptide (glycyl-L-histidyl-L-lysine) is about 200 ng/mL at age 20 and declines to about 80 ng/mL by age 60

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while making the skin more even and radiant