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Key members of this family include the membrane bound carboxylesterases CES1 and CES2 which are also present in the cytosol, along with arylacetamide deacetylase AADAC which is only found within the endoplasmic reticulum 16,17

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This causes a shift in the hemoglobin-oxygen dissociation curve to the left and an increased affinity of hemoglobin for oxygen