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This is a huge discovery — FOXO4-DRI is one of the most promising developments in anti-aging in a long time and is particularly exciting because it doesn’t just seem to slow down aging, it actually reverses it

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Most-cited animal HNG protocol The clearest reference point in the literature is HNG at 4 mg/kg, intraperitoneal, twice weekly , used in 18-month-old female C57BL/6N mice in the Yen et al