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Note that cuprizone application [232] was an extremely high regimen and much higher than those commonly applied to mimic multiple sclerosis in rats [243,244])

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This study revealed that NPI-001 (NACA), NPI-002 (diNACA) and NAC exhibited varying degrees of antioxidant activity, i.e., protected cultured rat retinal cells from a variety of stressors which were designed to mimic aspects of the pathology of different retinal diseases