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These radicals further react with PUFA-PLs to increase the yield of PLOOH ( This regulation is mediated mainly through two key proteins in the post-transcriptional network, IRP1 and IRP2, which regulate intracellular iron storage and release, as well as transfer and excretion ( in vivo further elucidated the important role of iron regulation in ferroptosis

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At higher doses (400+ mg magnesium for sleep, 40+ mg zinc for specific purposes), separating them by several hours is worthwhile

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