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In adaptive immunity, Rg1 stimulated CD4 + T-cell proliferation and antigen-specific IgG production, whereas Rh2 increased CD4 + /CD8 + T-cell infiltration and cytotoxicity in melanoma-bearing mice ( Recent results demonstrated that ginsenosides can effectively regulate the balance between T helper 1 (Th1) and T helper 2 (Th2) ( 3.5 Neuroprotective mechanisms of ginsenosides Ginsenosides exhibited neuroprotective properties by regulating oxidative stress, neuroinflammation, and neuronal survival pathways (Yin et al., 2024)