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The paper proposes, a final infusion rate of 12.5 mg/kg/h for a 32 g overdose, and a final infusion rate of 18.75 mg/kg/h for a 48 g overdose

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21 Among these precursors, NAM could be recycled from NAD + consumption reactions, including both NAD + -dependent deacylation and ADP-ribosylation, into NMN by NAMPT, which catalyzes the rate-limiting reaction in the salvage pathway