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These exosomal cargos regulate key implantation-related genes (HOXA10, LIF), inflammation, angiogenesis, and fibrosis, linking transcriptomic dysregulation to endometriosis pathophysiology and infertility ( 5.2 Immune and inflammatory markers Chronic inflammation and immune dysfunction are hallmark features of endometriosis, contributing to disease development and progression, with evidence from frequent co-occurrence with autoimmune diseases

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Intestinal barrier: an interface between health and disease