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Higher NAD+ activates the sirtuin family of NAD+-dependent deacetylases, particularly SIRT1, which deacetylates PGC-1alpha (promoting mitochondrial biogenesis), FOXO transcription factors (enhancing stress resistance), and NF-kappaB (reducing inflammation)

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Grundsätzlich lassen sich Peptid-Produkte jedoch in zwei Gruppen einteilen: Zum einen zugelassene Medikamente wie GLP-1-Analoga oder Insulin, deren Nebenwirkungen gut untersucht und dokumentiert sind